Introduction

BERBERINE CHLORIDE 97% is a high-purity crystalline alkaloid that resolves dosage consistency issues in metabolic and gastrointestinal formulations, providing a standardized, methanol-free active for pharmaceutical-grade supplements.

Specification

Appearance	Yellow powder
Specifications	97%
Composition	Berberine powder
Source	Coptis chinensis root
Level	Food grade
Alias	Berberine HCL
C A S No.	141433-60-5
EINECS	218-229-1
Molecular formula	C20H18ClNO4
Molecular Weight	336.36

COA

Item	Test Standard	Testing Result
Appearance	Powder	Complies
Color	Yellow powder	Complies
Particle Size	100% pass 80 mesh	Complies
Oder	Characteristic	Complies
Taste	Characteristic	Complies
Loss on Drying	≤5.0%	2.20%
Residue on Ignition	≤0.1%	0.05%
Residual acetone	≤0.1%	Complies
Residual Ethanol	≤0.5%	Complies
Heave Mentals	≤10ppm	Complies
Na	≤0.1%	<0.1%
Pb	≤3 ppm	Complies
Total Plate	<1000CFU/g	Complies
Yeast & Mold	<100 CFU /g	Complies
E. Coli	Negative	Complies
Salmonella	Negative	Complies
Conclusion: Conform with USP Standard

Key Features

Triple Crystallization

Proprietary re-crystallization removes Palmatine and related alkaloids to ensure consistent potency and prevent unintended chemical interactions in complex formulas.

Methanol-Free

Water and food-grade ethanol extraction verified by GC-MS ensures zero methanol residue for seamless US and EU regulatory compliance.

High Flowability

Uniform 80–100 mesh crystals prevent caking and optimize high-speed encapsulation for consistent fill weights and zero machine downtime.

Low Heavy Metals

USP <2232> compliance via ICP-MS testing guarantees elemental impurities remain far below international safety limits for Clean Label products.

Customization Options

Purity Range

95% / 97% / 98% / 99%

Particle Size

Crystal / 80–100 mesh / Micronized powder

Crystal Form

Standard / Optimized crystallization

Specification Control

Standard COA / Customized testing parameters

Residual Limits

Standard / Tightened (heavy metals & solvents)

Documentation

COA / MSDS / Export compliance files

Applications

Nutraceuticals

The gold standard for Blood Sugar Support and Metabolic Health supplements

Pharmaceuticals

Used as an API for anti-inflammatory and gastrointestinal medications.

Functional Foods

Increasingly used in advanced health blends targeting cardiovascular wellness.

Logistics & Packaging

01.

Standard Packaging

25kg/Fiber Drum with double PE inner liners.

02.

Storage

Store in a cool, dry place away from direct sunlight.

03.

Shelf Life

24 months when properly stored.

04.

Shipping

Global express or sea freight available (US/EU/Asia).

Shipment

Payment

Package

FAQ

Q: How do you ensure batch-to-batch consistency?

A: Every batch is tested using Agilent HPLC. We control the raw material source and use an automated crystallization system to minimize human error.

Q: Is your Berberine HCL suitable for vegan capsules?

A: Yes. Our extraction is 100% botanical-based with no animal-derived processing aids, making it fully suitable for Vegan and Vegetarian formulations.

Q: Do you offer micronized powder?

A: Yes, we can provide customized particle sizes (e.g., 200 mesh) for specific applications like liquid suspensions or rapid-release tablets.

Q: What is the main production process?

A: It is produced through extraction, purification, multi-stage crystallization, and drying.

Q: Do you provide samples?

A: Yes. Samples are available for quality testing before bulk order confirmation.

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Berberine Chloride 97%